Molecular Biology of the Cell, 6th Edition
نویسندگان
چکیده
Knowlton talks about the phenomenal biodiversity found in coral communities and why this diversity is important to reef health. She explains how difficult it is to classify corals and the many organisms with which they co-exist. Meyerowitz and his lab use live imaging techniques to study the positioning and growth of leaves and flowers. Remarkably, cells have the ability to sense mechanical forces produced by surrounding cells and respond accordingly by redistributing structural and growth proteins. Dr. Lindquist explains the problem of protein folding. Proteins leave the ribosome as long, linear chains of amino acids but they need to fold into complex three dimensional shapes in the extremely crowded environment of the cytoplasm (The Shape and Structure of Proteins) Length: 00:20:27 Neurodegenerative disease: The Coming Epidemic: Gregory Petsko The brains of patients with Alzheimer's, Parkinson's, and ALS/Lou Gehrig's diseases are characterized by the presence of protein aggregates due to protein misfolding. Petsko describes mechanisms that provide insight into potential treatments. Using computer programming, Baker and colleague are able to design an amino acid sequence that will fold into a predicted protein structure. This technique has potentially practical uses in the treatment of infection. In this talk, Ranganathan discusses the way that proteins spontaneously fold into complex 3 dimensional structures in order to fulfill their biochemical functions. When a growth factor binds to the plasma membrane of a quiescent cell, an intracellular signaling pathway is activated telling the cell to begin growing. Wittinghofer discusses the mechanisms of this growth-signaling pathway.
منابع مشابه
The 15th Iranian National Congress of Biochemistry & 6th International Congress of Biochemistry and Molecular Biology
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The latest edition maintains the excellence and appeal of the previous editions. Its clear text and outstanding illustrations, together with the complementary problems book make this an essential companion for students and lecturers alike.
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